Malwarebytes Anti-Malware is a great program for anti-malware protection.  It boasts the ability to thoroughly remove even the most advanced malware using a built in protection monitor that blocks malicious processes before they even start.  With the latest version they included an IP blocking feature that will prevent a user from visiting a potentially dangerous website.  Also, if a Trojan is executed on an infected system and it tries to download a payload, that payload will be BLOCKED by the IP blocking module.

However, the popups get annoying after a while and there is no built in feature to block the balloon notifications.  Here’s a fix to hide the annoying popup balloon notifications.  Right click on the start button and do properties. Make sure you’re on the task bar tab and next to “hide inactive icons” click the customize button. Then find Malwarebytes program and do  “always hide”.  This will prevent the notifications from popping up and annoying you but will still allow the program to run in the background.